”
Polimyxin B Analogs for LPS Detoxification
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Broad-Spectrum LPS Based vaccines of unencapsulated strains of Haemophilus Influenzae and other Pathogenic species of Gram-Negative Bacteria
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Endotoxin neutralizing Peptides
”
Structure-Function Studies of Antimicrobial and Endotoxin Neutralizing Peptides
Sylvie E. Blondelle, Jerala R., Lamata M., Moriyon I., Brandenburg K., Andrἅ J., Porro M., Lohner K.
Peptide Revolution: Genomics, Proteomics & Therapeutics American Peptide Society (2003).
”
Influence of synthetic antiendotoxin peptides on lipopolysaccharide (LPS) recognition and LPS-induced proinflammatory cytokine responses by cells expressing membrane-bound CD14
Iwagaki A., Porro M., Pollak M.
Infection and Immunity, Vol. 68, (3), 1655-1663, (2000).
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LPS/lipid A binding synthetic peptides
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A model of Neisseria Meningitidis vaccine based on LPS micelles detoxified
by synthetic anti-endotoxin peptides
Velucchi M., Rustici A., Meazza C., Villa P., Ghezzi P., Tsai C-M., Porro M.
Journal of Endotoxin Research, Vol. 4(4), 261-272, (1997).
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Neisseria Meningitidis LOS micelle-based vaccine
”
Natural and synthetic polypeptides that recognize the conserved lipid A
binding site of lipopolysaccharides
Porro M., Rustici A., Velucchi M., Agnello D., Villa P., Ghezzi P.
Endotoxin and sepsis: Molecular mechanism of pathogenesis, host resistance and therapy,
John Wiley & Sons, New York, 316-324 (1996).
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Inhibition of LPS-induced systemic and local TNF production by
a synthetic anti-endotoxin peptide (SAEP-2)
Demitri M.T., Velucchi M, Bracci L, Rustici A, Porro M., Villa P., Ghezzi P.
Journal of Endotoxin Research, Vol. 3(6), 445-454, (1996).
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Group of peptides that act sinergistically with hydrophobic antibiotics against
Gram-negative enteric bacteria
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Cyclic or linear conformations of sequences binding lipid A: does it really matter?
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Structural basis of endotoxin recognition by natural polypeptides
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Molecular Requirements of Peptide Structures Binding to the Lipid-A
Region of Bacterial Endotoxins
Velucchi M., Rustici A., Porro M.
Vaccines '94, Cold Spring Harbor Laboratory Press, 141-146, (1994).
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Molecular Mapping and Detoxification of the Lipid A Binding Site by Synthetic Peptides
Rustici A., Velucchi M., Faggioni R., Sironi M., Ghezzi P., Quataert S., Green B., Porro M.
Science, Vol. 259, 361-365, (1993).
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