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Intellectual Properties

Patents and Know How

The real value of the company, in addition to its People, are its Intellectual Properties, namely the Patents of Invention and their Technological Know-How. Over the course of 30 years of activity, BiosYnth has developed a total of 18 patents, some of which were then licensed to third parties. The IP/KH portfolio of BiosYnth currently includes various patents focused on fundamental vaccines for more efficient immunological response in pediatric age.

  • Patents issued in the field of Glycoconjugate Technology
  • Patents issued in the field of “SAEP” Technology (synthetic anti-endotoxin peptides)
  • Patents application in the field of antibiotic-resistant diseases (MDR)
  • Patents application in the field of sub-unit vaccines for viruses and bacteria (VS)
GLYCOPROTEINIC CONJUGATES
  • PATENT N° : USA 4,711,779
  • INVENTORS Massimo Porro, Paolo Costantino
  • ASSIGNEE Sclavo Spa, Siena, IT
  • APPL.N.: 881,091
  • GRANTED : Dec. 8,1987
OLIGOSACCHARIDE CONJUGATE VACCINES
  • PATENT N° : USA 5,153,312
  • INVENTORS Massimo Porro
  • ASSIGNEE American Cyanamid Co., N.J.
  • APPL.N.: 590,649
  • GRANTED : Oct. 6, 1992
OLIGOSACCHARIDE CONJUGATE VACCINES
  • PATENT N° : USA 5,306,492
  • INVENTORS Massimo Porro
  • ASSIGNEE American Cyanamid Co., N.J.
  • APPL.N.: 921,678
  • GRANTED : April 26,1994
SYNTHETIC PEPTIDES
  • PATENT N° : USA 5,358,933
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 49,871
  • GRANTED : Oct. 25, 1994
SYNTHETIC PEPTIDES
  • PATENT N° : USA 5,371,186
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 819,893
  • GRANTED : Dec. 6, 1994
SYNTHETIC PEPTIDES
  • PATENT N° : USA 5,589,459
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 280,397
  • GRANTED : Dec. 31, 1996
PEPTIDES FOR NEUTRALIZING THE TOXICITY OF LIPID A
  • PATENT N° : USA 5,652,211
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 97,830
  • GRANTED : July 29, 1997
POTENTIATION OF ANTIBIOTICS
  • PATENT N° : USA 5,834,430
  • INVENTORS Massimo Porro, Martti Varra
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 456,112
  • GRANTED : Nov. 10,1998
SYNTHETIC PEPTIDES
  • PATENT N° : EP 0623144 B1
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 92910229.1
  • GRANTED : Jan. 23, 2002
VACCINE FOR PREVENTION OF GRAM-NEGATIVE BACTERIAL INFECTIONS
  • PATENT N° : USA 6,951,652 B2
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 09/124,280
  • GRANTED : Oct. 4, 2005
IMPROVED POLYSACCHARIDE AND GLYCOCONJUGATES VACCINES
  • PATENT N° : EP 1501542 B1
  • INVENTORS Massimo Porro
  • ASSIGNEE Biosynth srl, IT
  • APPL.N.: 03749887,0
  • GRANTED : Aug. 22, 2007
POLYSACCHARIDE AND GLYCOCONJUGATE VACCINES
  • PATENT N° : USA 7588765 B2
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 10/513, 178
  • GRANTED : Sep. 15, 2009
POLIMYXIN B ANALOGS FOR LPS DETOXIFICATION
  • PATENT N° : USA 7,507,718 B2
  • INVENTORS Massimo Porro, Alessandro Rustici, Massimo Velucchi
  • ASSIGNEE Sanofi Pasteur, BiosYnth srl IT
  • APPL.N.: 11/398,915
  • GRANTED : March 24, 2009
ANTIMICROBIAL PEPTIDES
  • PATENT N° : USA 7,960,339 B2
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 12/373,272
  • GRANTED : Jan. 14,2011
GLYCOCONJUGATE VACCINES
  • PATENT N° : EP 3174553 B1
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 15742232.0
  • GRANTED : April 18,2018
MULTIVALENT GLYCOCONJUGATE VACCINES
  • PATENT N° : US 10,300,135 B2
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • APPL.N.: 14/764,953
  • GRANTED : May 28,2019
NANOSTRUCTURE-BASED VECTOR SYSTEM FOR BACTERIAL AND VIRAL ANTIGENS
  • PATENT N° : 63/306,459
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • FILED : Feb 3, 2022
NANOSTRUCTURED-BASED VECTOR SYSTEM FOR BACTERIAL AND VIRAL ANTIGENS
  • PATENT N° : PCT/ IB 2023/ 050902
  • INVENTORS Massimo Porro
  • ASSIGNEE BiosYnth srl, IT
  • FILED : Feb 2, 2023
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