Intellectual Properties
Patents and Know How
The real value of the company, in addition to its People, are its Intellectual Properties, namely the Patents of Invention and their Technological Know-How. Over the course of 30 years of activity, BiosYnth has developed a total of 18 patents, some of which were then licensed to third parties. The IP/KH portfolio of BiosYnth currently includes various patents focused on fundamental vaccines for more efficient immunological response in pediatric age.
- Patents issued in the field of Glycoconjugate Technology
- Patents issued in the field of “SAEP” Technology (synthetic anti-endotoxin peptides)
- Patents application in the field of antibiotic-resistant diseases (MDR)
- Patents application in the field of sub-unit vaccines for viruses and bacteria (VS)

GLYCOPROTEINIC CONJUGATES
- PATENT N° : USA 4,711,779
- INVENTORS Massimo Porro, Paolo Costantino
- ASSIGNEE Sclavo Spa, Siena, IT
- APPL.N.: 881,091
- GRANTED : Dec. 8,1987

OLIGOSACCHARIDE CONJUGATE VACCINES
- PATENT N° : USA 5,153,312
- INVENTORS Massimo Porro
- ASSIGNEE American Cyanamid Co., N.J.
- APPL.N.: 590,649
- GRANTED : Oct. 6, 1992

OLIGOSACCHARIDE CONJUGATE VACCINES
- PATENT N° : USA 5,306,492
- INVENTORS Massimo Porro
- ASSIGNEE American Cyanamid Co., N.J.
- APPL.N.: 921,678
- GRANTED : April 26,1994

SYNTHETIC PEPTIDES
- PATENT N° : USA 5,358,933
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 49,871
- GRANTED : Oct. 25, 1994

SYNTHETIC PEPTIDES
- PATENT N° : USA 5,371,186
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 819,893
- GRANTED : Dec. 6, 1994

SYNTHETIC PEPTIDES
- PATENT N° : USA 5,589,459
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 280,397
- GRANTED : Dec. 31, 1996

PEPTIDES FOR NEUTRALIZING THE TOXICITY OF LIPID A
- PATENT N° : USA 5,652,211
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 97,830
- GRANTED : July 29, 1997

POTENTIATION OF ANTIBIOTICS
- PATENT N° : USA 5,834,430
- INVENTORS Massimo Porro, Martti Varra
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 456,112
- GRANTED : Nov. 10,1998

SYNTHETIC PEPTIDES
- PATENT N° : EP 0623144 B1
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 92910229.1
- GRANTED : Jan. 23, 2002

VACCINE FOR PREVENTION OF GRAM-NEGATIVE BACTERIAL INFECTIONS
- PATENT N° : USA 6,951,652 B2
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 09/124,280
- GRANTED : Oct. 4, 2005

IMPROVED POLYSACCHARIDE AND GLYCOCONJUGATES VACCINES
- PATENT N° : EP 1501542 B1
- INVENTORS Massimo Porro
- ASSIGNEE Biosynth srl, IT
- APPL.N.: 03749887,0
- GRANTED : Aug. 22, 2007

POLYSACCHARIDE AND GLYCOCONJUGATE VACCINES
- PATENT N° : USA 7588765 B2
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 10/513, 178
- GRANTED : Sep. 15, 2009

POLIMYXIN B ANALOGS FOR LPS DETOXIFICATION
- PATENT N° : USA 7,507,718 B2
- INVENTORS Massimo Porro, Alessandro Rustici, Massimo Velucchi
- ASSIGNEE Sanofi Pasteur, BiosYnth srl IT
- APPL.N.: 11/398,915
- GRANTED : March 24, 2009

ANTIMICROBIAL PEPTIDES
- PATENT N° : USA 7,960,339 B2
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 12/373,272
- GRANTED : Jan. 14,2011

GLYCOCONJUGATE VACCINES
- PATENT N° : EP 3174553 B1
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 15742232.0
- GRANTED : April 18,2018

MULTIVALENT GLYCOCONJUGATE VACCINES
- PATENT N° : US 10,300,135 B2
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- APPL.N.: 14/764,953
- GRANTED : May 28,2019

NANOSTRUCTURE-BASED VECTOR SYSTEM FOR BACTERIAL AND VIRAL ANTIGENS
- PATENT N° : 63/306,459
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- FILED : Feb 3, 2022

NANOSTRUCTURED-BASED VECTOR SYSTEM FOR BACTERIAL AND VIRAL ANTIGENS
- PATENT N° : PCT/ IB 2023/ 050902
- INVENTORS Massimo Porro
- ASSIGNEE BiosYnth srl, IT
- FILED : Feb 2, 2023